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Digital Tools to Improve Outcomes

Life Sciences Companies

Looking to generate real world evidence, increase patient engagement and more? 


Looking to improve patient outcomes, enhance workflow, and increase profitability?

Life sciences companies are under enormous pressure to demonstrate value with payors and increasingly, prescribers and patients. We help life sciences companies improve the value of their pipeline and brands by creating and leveraging digital technologies to generate real-world evidence (RWE) and insights directly from patients. We do so by utilizing our proprietary software solutions as well as Smartphones, Smart Speakers, wearable sensors, and in-home stationary sensors.


We can help you:

        Receive approval for label changes or new indications
        Improve the safety and efficacy of a drug for new populations
        Demonstrate the superiority of your brand vs. competitors
        Better understand patients’ experiences and voice, including unmet burden
        Improve quality of life
        Reduce total cost of care
        Increase adherence
        Better manage side effects
        Reduce healthcare provider burden re: managing patients

Life Sciences

Life Sciences

Life Sciences

ePRO Platform

Our ePRO platform, which employs a bring-your-own-device (BYOD) approach, enables subjects to quickly and easily fill out any validated instrument or custom questionnaire. We also activate patients to enter data through engaging notifications and reminders. All data is gathered in real time and transmitted and stored in our secure cloud environment.


Our ePRO platform enables sponsors to measure:

Disease-specific, health-related quality of life

General health-related quality of life

Health utilities measurements

Patient preference and/or satisfaction

Symptom scores

Patient or informal caregiver burden

Data is then accessed by the Pharma sponsor, the CRO or us in a secure manner. Data is formatted to be compatible with all clinical trial software.



CarePrompter is a software platform that sponsors can use to improve study outcomes. Available as a Smartphone and tablet application, study teams can download CarePrompter onto subjects’ devices and train them how to use the software to report symptoms/side effects and other key data in real time. The application can also be customized to encourage patients to engage in enhanced self-care. 


All of this data can be monitored by study nurses via intuitive dashboards or securely sent to the EHRs of relevant clinicians who can then make nuanced interventions re: side effects, adherence, questions and concerns. These actions can help sponsors reduce patient dropout and reduce high grade symptoms and adverse events all while improving quality of life, patient satisfaction and clinical outcomes. 

CarePrompter can also be used to power patient support programs. Patients can review instructions, educational content, report and track symptoms, and engage in other activities.

Check out how CarePrompter works at the Astellas C3 Finalist Competition. 








CarePrompter is a nurse triage platform and patient engagement tool. CarePrompter has
improved healthcare outcomes for oncology patients across the United States. Built with patients and clinicians in mind, our product enables oncology departments and
practices to provide personalized care and reduce costs through increased efficiency.​ 

Patients download CarePrompter onto their smartphones, which enables them to:​

Engage in self-care

Report symptoms

Fill out QoL and other validated instruments

Track their health over time


Patient data can be securely transmitted to nurses who access it via the myCare Dashboard integrated into the EHR.


Practices can customize CarePrompter in many ways, including:

Educational content

Question branching logic

Clinician-facing triage protocol and alerts

Any validated or custom instrument

Doctor Examining Female Patient With Elb

Digidence develops state-of-the-art software tools for oncology departments and practices to improve patient outcomes, enhance workflow, and increase profitability. Through clinical collaborations across the United States, our products are expertly designed, scientifically tested, and fully utilized by clinicians and patients.

In Good Hands



National Science Foundation

Phase I and II

Digidence is the proud recipient of two National Science Foundation grants. Both awards partially supported the development and validation of CarePrompter. 
CarePrompter enables subjects to engage in self-care and provides decision support to clinicians to better control symptom side effects.


National Cancer Institute

Phase I and II

For NCI, we are currently developing Caregiver Buddy, a software technology to enable informal caregivers to render better care to their loved ones. Caregiver Buddy also helps informal caregivers, who frequently suffer from depression, anxiety and other issues, improve their own health.


University of

Machine Learning

We engaged in joint research with the University of Michigan to create and enhance a variety of machine learning algorithms to predict fatigue and sleeplessness in fibromyalgia patients using wearable sensors. 

The results? The custom model's accuracy and AUROC were much higher than conventional models. 

This research could help clinicians make better treatment decisions as well as help device and pharmaceutical manufacturers devise improved products.

Check out the study


Working with leading clinical collaborators, we are a group of passionate health information technology professionals who help life science companies improve their value propositions by generating compelling RWE.



Amine Raounak


Amine is a veteran of AOL, Capital One, United States Digital Service and other leading organizations.

Amine has played key roles in software development, security, architecture and integration. He is the author of two patents and

received his M.I.S. from Virginia

International University.


Howard Isenstein


Howard has extensive experience in quality improvement and health information technology through key roles at the Federation of American Hospitals, Booz Allen Hamilton, and Walgreen’s. Howard completed post-graduate work at Johns Hopkins University.


Brandon Govindarajoo

Chief Data Scientist

Brandon has extensive data science experience in life sciences and completed his Ph.D. in bioinformatics from the University of Michigan.

Business Advisory Board


Daniel Gold

Chief Operating Officer, Life Matters

Daniel Gold has pioneered, grown and led businesses from start-ups to mature entities in the healthcare services, pharmaceutical, and technology sectors. Currently he serves as EVP of, a national provider of home care services for the elderly.

Clinical Advisory Board


John Marshall, MD

John Marshall, MD, is a global leader in the research and development of drugs for colon cancer and other GI cancers. He is the principal investigator of over 150 clinical trials, at the local as well as the national level. Dr. Marshall is the clinical director of oncology for Georgetown University Hospital, associate director for clinical care of the Lombardi Comprehensive Cancer Center, and chief of the Division of Hematology-Oncology. He is widely published in the field of clinical oncology, reviews manuscripts for eight journals, and holds peer-reviewed grants from the National Institutes of Health.
In 2009, Dr. Marshall became the founding director of the Otto J. Ruesch Center for the Cure of Gastrointestinal Cancer. Combining expertise in molecular medicine, translational research, and a patient-centered philosophy, the Ruesch Center is dedicated to realizing the dream of individualized curative therapies through research, care and advocacy.


Martin E. Gutierrez, MD

Dr. Martin Gutierrez is the director of Drug Discovery and Phase I Unit at John Theurer Cancer Center at Hackensack University Medical Center. Dr. Gutierrez specializes in medical oncology, thoracic and gastrointestinal oncology, and is board certified in internal medicine, medical oncology and hematology.

Dr. Gutierrez is a member of the American College of Physicians, Massachusetts Medical Society, American Society of Clinical Oncology, American Association for Cancer Research, American Society of Hematology, National Surgical Adjuvant Breast and Bowel Project, Cancer and Leukemia Group B, Radiation Therapy Oncology Group, and Cancer Trials Support Unit. He is a reviewer for the scientific journals Clinical Cancer Research, The Cancer Journal and Cancer Chemotherapy and Pharmacology.


Marc Overhage, MD

Dr. J. Marc Overhage, Vice President and Chief Medical Informatics Officer, is responsible for leading intelligence strategy for Cerner. He collaborates with leaders across the company and industry to enhance Cerner’s industry-leading solutions. Marc focuses on making Cerner’s solutions more intelligent building on national standards, evolving machine learning techniques and data-driven strategies.


Dr. Overhage has more than 25 years of experience developing and implementing clinical and scientific systems and evaluating their value. Prior to Cerner, Dr. Overhage was the Director of Medical Informatics at the Regenstrief Institute, Inc. and the Sam Regenstrief Professor of Medical Informatics at the Indiana University School of Medicine.


We offer a focused range of services to add value to Sponsors’ brands and pipeline.



Study design, implementation, analysis and publication

We design and implement Interventional, Observational and Pragmatic studies to better understand patient and informal caregiver perspectives.

In order to conduct these studies we employ our current software solutions or create custom software applications to be used in tandem with Smartphones, wearable or fixed sensors, smart speakers or other data collection devices. 

Site Network

Site network and recruitment

Through our relationships with major hospitals, including Rush University Medical Center, MedStar Health, Christus Health and Hackensack University Medical Center, we can recruit subjects with a range of conditions, including in Oncology and CNS.


Data analysis and machine learning

We have extensive experience in bioinformatics, including research using machine learning techniques. For example, we created a model to predict fatigue and sleeplessness in fibromyalgia patients using a customized machine learning  algorithm superior to conventional methods. 


We’re growing! Please check out our current openings. If you don’t see something you like, please check us out later. To apply, please email with the position you’re interested in within the subject of your email and send your resume to us at



Contact Us

6900 Wisconsin Ave.

Suite 217

Bethesda, MD 20815

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